产品类别
兔抗人、大、小鼠β3-肾上腺素能受体抗体
产品价格
0.1ml/480元 0.2ml/650元
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
产品介绍
ARβ3是新近发现的,继β1和β2之后的第3个β型肾上腺素受体亚型.分子量：44KDa(404AA)
近年来研究表明:β3-肾上腺素受体该受体基因突变或基因多态性与机体肥胖及心血管疾病相关;心力衰竭时该受体的含量明显增加,β3肾上腺素能受体与心血管疾病的相关研究可能为心血管疾病的预测、防治的新方法.
beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.
mol wt:44kDa
Other Aliases:
β3-adrenergic receptor;β3-AR; adrenergic;beta-3- receptor; ADR B3 ; ADRB 3; ADRB3; ADRB3R; Adrenergic beta 3 receptor; B3AR; Beta 3 adrenoceptor; Beta 3 adrenoreceptor; Beta 3AR; B3AR; BETA3AR
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