产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

    ADRA1肾上腺素能α1受体位于突触后，在血管平滑肌上，兴奋时可使血管收缩;
    alpha 1-adrenergic receptor有兴奋效应也有抑制效应。肾上腺素能受体又可分为α和β两种。alpha 受体与儿茶酚胺结合后，主要是兴奋平滑肌，如血管收缩、子宫收缩和瞳孔开张肌收缩等；但也有抑制作用，如使小肠平滑肌舒张。β受体又可分为β1和β2两个亚型
    Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.
    mol wt:57kDa
    Other Aliases:
    ADRA1; ADRA1A; ADRA1B; ADRA1C; ADRA1D; ADRA1L1; ADRA1R; Adrenergic alpha 1A receptor; Adrenergic alpha 1B receptor; Adrenergic alpha 1C receptor; Adrenergic alpha 1D receptor; Alpha 1A adrenergic receptor; Alpha 1A adrenoceptor; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor; Alpha 1D adrenergic receptor; Alpha 1D adrenoceptor; Alpha 1D adrenoreceptor; Alpha adrenergic receptor 1a; Alpha adrenergic receptor 1b; Alpha adrenergic receptor 1c; Alpha adrenergic receptor 1d; Alpha1; ALPHA1AAR; DAR; dJ779E11.2