产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
CD26是细胞表面上一种氨基肽酶,具有丝氨酸蛋白酶活性,属于丝氨酸蛋白酶s9b家族,分布于多种细胞表面或游离于胞浆中,具有高度保守的蛋白水解酶活性. 还是一种细胞膜受体、共刺激分子,参与机体免疫调节、细胞迁移、细胞黏附和细胞凋亡。
CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection
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