产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
降钙素是甲状腺滤泡旁细胞(C细胞)分泌的含有32个氨基酸的单链多肽,可使血钙、磷水平降低的一种多肽激素 ,脑组织和垂体含有降钙素,前列腺等其他组织也存在CT。主要用于C细胞增生和甲状腺髓样癌的诊断、也可用于其他类型的神经内分泌肿瘤的研究分子量为3.5 kDa。
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity. mol wt:15kDa Other Aliases: Alpha CGRP; CALC 1; CALC A; CALC1; CALCA; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP1; CGRPI; CT; Katacalcin; KC; MGC126648
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