产品类别

 兔抗人、大、小鼠、牛、羊、猪G-CSF粒细胞集落刺激因子抗体

产品价格

 0.1ml/480元  0.2ml/650元  

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 

产品介绍

  生长因子和激素（ Growth Factor and Hormones） 
  集落刺激因子是一组功能很强的骨髓造血细胞增殖因子，GCSF（粒细胞克隆刺激因子）为其中一种，具有刺激粒系母细胞的增殖和分化，并可增强成熟粒细胞功能的作用。粒细胞集落刺激因子在抗感染的非特异性细胞免疫过程中起重要作用。
  Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-γ. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body.
    mol wt:19kDa
    Other Aliases:
    Colony stimulating factor 3 (granulocyte); CSF 3 ;CSF beta; CSF3; Csfg; Filgrastim; GCSA; GCSF; Granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin