产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

    PAK7通过影响NFκB信号通路而抑制细胞凋亡、影响细胞骨架形成、促进细胞的生长、发育，是NFκB信号通路的重要调控蛋白.

    PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.
    mol wt:79kDa
    Other Aliases:
    Mbt; mushroom bodies tiny; CG18582; Dmel\CG18582; DmMBT; DmPAK2; dPAK2; Mbt; Pak2; Ste20; STE20; Serine/threonine-protein kinase PAK mbt; Protein mushroom bodies tiny; p21-activated kinase-related protein; LD47563p; Ste20 serine/threonine protein kinase homolog; GG19059; GM13449; GE17281; 2900083L08Rik; 6430627N20; MGC117585; Serine/threonine-protein kinase PAK 7; 2900083L08Rik; 6430627N20; MGC117585; Pak5; PAK7; p21-activated kinase 5; P21 protein (Cdc42/Rac)-activated kinase 7