产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
产品介绍
细胞粘附蛋白（Call Adhesion Protein）
上皮膜抗原是粘性糖蛋白家族之一,是一种膜内在糖蛋白。Muc-1表达仅限于内膜腺上皮和腔上皮,很多上皮细胞及其来源的肿瘤表达该蛋白.
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It
also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
Gene Symbol:
Epithelial Membrane Antigen; Episialin; episialin; MUC1; MUC1/ZD; MUC-1/X; PEMT; MUC-1; MUC-1/SEC; PUM; EMA; PEM; H23AG; MAM6; CD227; CD227 antigen; Mucin-1 precursor; MUC-1; Polymorphic epithelial mucin; PEM; PEMT; Tumor-associated mucin; Carcinoma-associated mucin; Tumor-associated epithelial membrane antigen;Breast carcinoma-associated antigen DF3
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